Anthracyclin derivatives

The present invention relates to anthracyclin derivatives of the formula I (I) in which R1 and R2 are identical or different and represent the sugar residue Roa (L-rhodosamine) of the formula or the sugar combination Roa-dF=CinB (dF=2-deoxy-L-fucose; CinB=L-cinerulose B) of the formula The invention...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	BERSCHEID, HANS G, HUBER, GERHARD, FEHLHABER, HANS-WOLFRAM, KRAEMER, HANS P
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY DERIVATIVES THEREOF ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS SUGARS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to anthracyclin derivatives of the formula I (I) in which R1 and R2 are identical or different and represent the sugar residue Roa (L-rhodosamine) of the formula or the sugar combination Roa-dF=CinB (dF=2-deoxy-L-fucose; CinB=L-cinerulose B) of the formula The invention furthermore relates to a process for the preparation of the above compounds of the formula I, and to their use as cytostatic agents.