Composition for detection of peritoneal inflammation or infection

Peritoneal inflammation or infection can be detected in a patient by assaying a peritoneal lavage sample from the patient for lysosomal enzymes. This is done by combining the lavage sample with a leukocyte lysing agent and a chromogenic or fluorogenic enzyme substrate specific for lysosomal enzymes....

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Hauptverfasser: BABB, JAMES L, BLOOMSTER, TIMOTHY G, RUDBACH, JON A
Format: Patent
Sprache:eng
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Zusammenfassung:Peritoneal inflammation or infection can be detected in a patient by assaying a peritoneal lavage sample from the patient for lysosomal enzymes. This is done by combining the lavage sample with a leukocyte lysing agent and a chromogenic or fluorogenic enzyme substrate specific for lysosomal enzymes. The lysosomal enzymes can then be measured, and the inflammation of infection detected, by measuring the color or fluorescence developed in the sample by action of the enzymes on the substrate.