Apparatus for multipolymer synthesis of organic compounds

A method and apparatus are provided for synthesizing organic compounds in which reactants A and B are bound to respective polymeric supports and P/ &cir& and P'/ &cir& . Reactant A is bound to P/ &cir& via a linking moiety alpha min and an intermediate reactant alpha is...

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Bibliographische Detailangaben
Hauptverfasser:	PASS, SHIMEON, SHAI, YECHIEL, PATCHORNIK, ABRAHAM
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM APPARATUS THEREFOR CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY CHEMISTRY COMBINATORIAL CHEMISTRY COMPOSITIONS BASED THEREON COMPOSITIONS OF MACROMOLECULAR COMPOUNDS DERIVATIVES THEREOF GENERAL METHODS OF ORGANIC CHEMISTRY HETEROCYCLIC COMPOUNDS LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY ORGANIC MACROMOLECULAR COMPOUNDS PEPTIDES PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL SUGARS THEIR PREPARATION OR CHEMICAL WORKING-UP THEIR RELEVANT APPARATUS TRANSPORTING
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Beschreibung
Zusammenfassung:	A method and apparatus are provided for synthesizing organic compounds in which reactants A and B are bound to respective polymeric supports and P/ &cir& and P'/ &cir& . Reactant A is bound to P/ &cir& via a linking moiety alpha min and an intermediate reactant alpha is circulated between the two polymeric supports. When alpha is fed to the first support alpha -A is formed and when alpha -A is fed to the second support P'/ &cir& -B-A is formed and free alpha regenerated. When sufficient P min -B-A is formed, the circulation is stopped and B-A separated and removed.