Heterocyclic derivatives

Heterocyclic derivatives

The invention relates to compounds of the general formula (I) (I) and physiologically acceptable salts, hydrates and bioprecursors thereof, in which Q represents a benzene ring in which incorporation into the rest of the molecule is through bonds at the 1- and 3- or 1- and 4- positions: Z represents...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: MACKINNON, JOHN W. M, HAYES, ROGER, BAYS, DAVID E
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The invention relates to compounds of the general formula (I) (I) and physiologically acceptable salts, hydrates and bioprecursors thereof, in which Q represents a benzene ring in which incorporation into the rest of the molecule is through bonds at the 1- and 3- or 1- and 4- positions: Z represents one of the groups where X represents NCN, NSO2Methyl, NSO2Phenyl or CHNO2. The compounds show pharmacological activity as selective histamine H2-antagonists.