Polymeric active methylene compounds, their preparation and their use in azo polymers

Polymeric active methylene compounds, their preparation and their use in azo polymers

Polymer compounds which have recurring units are disclosed. These polymers provide active methylene groups which serve as points of attachment for organic groups-particularly azo functionality-containing groups. These azo links can be cleaved by bacteria in the mammalian lower bowel, thereby releasi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: WANG, PATRICIA C, DAWSON, DANIEL J
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
COMPOSITIONS BASED THEREON
MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS
METALLURGY
ORGANIC MACROMOLECULAR COMPOUNDS
THEIR PREPARATION OR CHEMICAL WORKING-UP
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Beschreibung
Zusammenfassung:Polymer compounds which have recurring units are disclosed. These polymers provide active methylene groups which serve as points of attachment for organic groups-particularly azo functionality-containing groups. These azo links can be cleaved by bacteria in the mammalian lower bowel, thereby releasing the corresponding amino groups. This mechanism can effect programmed delivery of pharmaceutically desirable species to the lower bowel.