[1-(2-Benzoxazolyl)hydrazino]alkyl nitrile derivatives

Described are compounds of the formula wherein R is hydrogen or loweralkyl, X, Y and W independently of one another denote hydrogen, halogen, loweralkyl, nitro, amino, amido, loweralkoxy, hydroxy, nitrile, methylsulfone, methylsulfoxide, methylmercapto, or trifluoromethyl; Z is oxygen, sulfur or -CH...

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Hauptverfasser: RATAJCZYK, JAMES D, HAVIV, FORTUNA, FISCHER, FRANCIS E
Format: Patent
Sprache:eng
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Zusammenfassung:Described are compounds of the formula wherein R is hydrogen or loweralkyl, X, Y and W independently of one another denote hydrogen, halogen, loweralkyl, nitro, amino, amido, loweralkoxy, hydroxy, nitrile, methylsulfone, methylsulfoxide, methylmercapto, or trifluoromethyl; Z is oxygen, sulfur or -CH2; n and m are each an integer from 0 to 6 inclusive, or pharmaceutically acceptable salts thereof. The compounds are effective as anti-inflammatory agents.