Substituted (10H-phenothiazin-10-L)-propyl-1-piperazines

Substituted (10H-phenothiazin-10-L)-propyl-1-piperazines

Substituted (10H-phenothiazin-10-yl)propyl-1-piperazines of the formula I wherein R1, R2, R3, A, X, m, n and s are as hereinafter set forth, are described. The compounds of formula I, which contain a piperazine moiety combined by an ether linkage to different phenolic moieties, are useful as orally...

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Bibliographische Detailangaben
Hauptverfasser: DAVIDSON, ARNOLD B, GUTHRIE, ROBERT W, KIERSTEAD, RICHARD W, ZIERING, ALBERT
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Substituted (10H-phenothiazin-10-yl)propyl-1-piperazines of the formula I wherein R1, R2, R3, A, X, m, n and s are as hereinafter set forth, are described. The compounds of formula I, which contain a piperazine moiety combined by an ether linkage to different phenolic moieties, are useful as orally active long lasting antipsychotic agents.