Novel supports carrying side chains, processes for obtaining these supports, process for attaching organic compounds having carbohydrate residues one said supports, products and reagents resulting from said chemical fixation

Process for chemically binding organic compounds containing carbohydrate residues, onto a support bearing at least one reactive -NH2, in which at least one -CH2OH group of the carbohydrate residue is transformed in a -CHO group, by oxidation and then the -CHO groups thus obtained are reacted with at...

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Bibliographische Detailangaben
Hauptverfasser: QUASH, GERARD A
Format: Patent
Sprache:eng
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Zusammenfassung:Process for chemically binding organic compounds containing carbohydrate residues, onto a support bearing at least one reactive -NH2, in which at least one -CH2OH group of the carbohydrate residue is transformed in a -CHO group, by oxidation and then the -CHO groups thus obtained are reacted with at least a reactive -NH2 carried by the side chains covalently bound on a solid, insoluble support, the side chains are chosen from among amines, polyamines, diacids, amino-acids, hydrazines, and are eventually coupled, by the intermediary of their reactive -NH2, with a nitrogen-containing compound chosen from aliphatic or aromatic amines, aliphatic or aromatic hydrazines, or amino acids, comprising eventually jointly a -SH group and a -NH2 group. Products resulting from this process and biological reagents containing said products as their active constituents.