Formulation and method of making cationic lipophilic complexes

Formulation and method of making cationic lipophilic complexes

A method for the preparation of a technetium-99m complex having the formula [(L)299mTc(X)2](+)X(-), which comprises adding technetium-99m to a complex having the formula [(L)2M(X)2](+)X(-) and heating the mixture in the presence of a source of anion X(-), wherein each L is the same or different lipo...

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Hauptverfasser: NEIRINCKX, RUDI D
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:A method for the preparation of a technetium-99m complex having the formula [(L)299mTc(X)2](+)X(-), which comprises adding technetium-99m to a complex having the formula [(L)2M(X)2](+)X(-) and heating the mixture in the presence of a source of anion X(-), wherein each L is the same or different lipophilic ligand, each X is the same or different monovalent anionic ligand, and M is a non-toxic trivalent metal ion, is disclosed.