Amino-1-[(halophenyl)-lower-alkyl]piperidines

1-[(3- or 4-Benzoylphenyl)-lower-alkyl]-[(CH2)n-N=B]-substituted-piperidines useful as anti-asthmatic, anti-allergic, anti-cholinergic, bronchodilator and anti-inflammatory agents, are prepared by alkylation of an appropriate substituted piperidine with a (3- or 4-benzoylphenyl)-lower-alkyl halide or tosylate; by reaction of a 1-[2-(3- or 4-lithiophenyl)-lower-alkyl]-[(CH2)n-N=B]-substituted-piperidine with benzonitrile and hydrolysis of the resulting benzimidoyl compound; or by reduction of a 1-[ alpha -(3- or 4-benzoylphenyl)-lower-alkanoyl]-[(CH2)n-N=B]-substituted-piperidine. The analogous carbinols are prepared by reduction, with an alkali metal borohydride, of the ketone.