Oral male contraceptive composition

A male contraceptive composition is described that may be administered orally. This permits adjusting the dose of the constituents to provide for sperm production inhibition and for normal functioning of secondary sex glands to permit normal sexual activity without fertility. The constituents of the composition are gossypol or derivatives thereof for controlling the sperm production combined with an orally active replacement androgen for counteracting the effect of the gossypol or its derivatives upon secondary sex glands. Ranges of composition and discussions of test results are described together with the method of determining the dose levels needed to achieve the desired result. The composition may be preferably administered as a pill. A maintenance dose level may be utilized after azoospermia sperm levels are achieved.