Process for synthesizing estrone or estrone derivatives

What are disclosed are a multi-step synthesis for the preparation of 9(11)-dehydroestrone 3-methyl ether from 2-methyl,4-methoxy benzaldehyde; 1-(4-methoxy-2-methyl-(phenyl)-3-(1-methyl-2-oxo-5-t-vinyl-cyclopent-r -yl)-propane-1-one, an intermediate in said synthesis; and a method for the preparatio...

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Bibliographische Detailangaben
Hauptverfasser: QUINKERT, GERHARD, SCHWARTZ, ULRICH, WEBER, WOLF-DIETRICH
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:What are disclosed are a multi-step synthesis for the preparation of 9(11)-dehydroestrone 3-methyl ether from 2-methyl,4-methoxy benzaldehyde; 1-(4-methoxy-2-methyl-(phenyl)-3-(1-methyl-2-oxo-5-t-vinyl-cyclopent-r -yl)-propane-1-one, an intermediate in said synthesis; and a method for the preparation of 3-vinylcyclopentanone from 2-vinylcyclopropane-1,1-dicarboxylic acid.