3-Aryl-3-aryloxypropylamines

3-Aryl-3-aryloxypropylamines

3-Aryl-3-aryloxyalkylamines of the general formula (I) (I) and their pharmaceutically acceptable acid addition salts, wherein R1, R2, R4 and R5 are hydrogen or lower alkyl, R3 is hydrogen, lower alkyl or benzyl, Ar is phenyl optionally substituted by one or more halogen, trifluoromethyl, lower alkyl...

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Hauptverfasser: SHEPHERD, ROBIN G
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Sprache:eng
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ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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ROBIN G
description 3-Aryl-3-aryloxyalkylamines of the general formula (I) (I) and their pharmaceutically acceptable acid addition salts, wherein R1, R2, R4 and R5 are hydrogen or lower alkyl, R3 is hydrogen, lower alkyl or benzyl, Ar is phenyl optionally substituted by one or more halogen, trifluoromethyl, lower alkyl, lower alkoxy, nitro or amino groups, and Ar1 is methylsulphinyl, methylsulphonyl- or cyano-substituted phenyl, 2- or 4-pyridyl, 2-pyrazinyl, 2-quinolinyl, 2-thienyl or 2-thiazolyl exhibit activity on the central nervous system, e.g. as antidepressants.
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ROBIN G</creator><scope>EVB</scope></search><sort><creationdate>19820518</creationdate><title>3-Aryl-3-aryloxypropylamines</title><author>SHEPHERD; ROBIN G</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US4330546A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1982</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>SHEPHERD; ROBIN G</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SHEPHERD; ROBIN G</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>3-Aryl-3-aryloxypropylamines</title><date>1982-05-18</date><risdate>1982</risdate><abstract>3-Aryl-3-aryloxyalkylamines of the general formula (I) (I) and their pharmaceutically acceptable acid addition salts, wherein R1, R2, R4 and R5 are hydrogen or lower alkyl, R3 is hydrogen, lower alkyl or benzyl, Ar is phenyl optionally substituted by one or more halogen, trifluoromethyl, lower alkyl, lower alkoxy, nitro or amino groups, and Ar1 is methylsulphinyl, methylsulphonyl- or cyano-substituted phenyl, 2- or 4-pyridyl, 2-pyrazinyl, 2-quinolinyl, 2-thienyl or 2-thiazolyl exhibit activity on the central nervous system, e.g. as antidepressants.</abstract><oa>free_for_read</oa></addata></record>
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title 3-Aryl-3-aryloxypropylamines
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