3-Aryl-3-aryloxypropylamines

3-Aryl-3-aryloxyalkylamines of the general formula (I) (I) and their pharmaceutically acceptable acid addition salts, wherein R1, R2, R4 and R5 are hydrogen or lower alkyl, R3 is hydrogen, lower alkyl or benzyl, Ar is phenyl optionally substituted by one or more halogen, trifluoromethyl, lower alkyl...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: SHEPHERD, ROBIN G
Format: Patent
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:3-Aryl-3-aryloxyalkylamines of the general formula (I) (I) and their pharmaceutically acceptable acid addition salts, wherein R1, R2, R4 and R5 are hydrogen or lower alkyl, R3 is hydrogen, lower alkyl or benzyl, Ar is phenyl optionally substituted by one or more halogen, trifluoromethyl, lower alkyl, lower alkoxy, nitro or amino groups, and Ar1 is methylsulphinyl, methylsulphonyl- or cyano-substituted phenyl, 2- or 4-pyridyl, 2-pyrazinyl, 2-quinolinyl, 2-thienyl or 2-thiazolyl exhibit activity on the central nervous system, e.g. as antidepressants.