Phenylaminothiophenacetic acids, their synthesis, compositions and use

Phenylaminothiophenacetic acids of formula I (I) wherein R1 denotes a hydrogen atom, a chlorine atom, a bromine atom or a methyl group, R2 denotes a -CH2-COOH group or a -CH2-COOR6 group, R3 denotes a hydrogen atom, a halogen atom, an alkyl group, an alkoxy group or a trifluoromethyl group, R4 has o...

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Sprache:eng
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Zusammenfassung:Phenylaminothiophenacetic acids of formula I (I) wherein R1 denotes a hydrogen atom, a chlorine atom, a bromine atom or a methyl group, R2 denotes a -CH2-COOH group or a -CH2-COOR6 group, R3 denotes a hydrogen atom, a halogen atom, an alkyl group, an alkoxy group or a trifluoromethyl group, R4 has one of the meanings of R3, R5 denotes a hydrogen atom, a halogen atom or an alkyl group, R6 denotes an alkyl group (with from 1 to 5 carbon atoms), which is optionally substituted by hydroxyl, hydroxyalkoxy or alkanoyloxy groups, or a benzyl group and n denotes 1 or 2, and salts of the acids have outstanding antiphlogistic, analgesic and antipyretic activities.