Method of fractional quantitative determination of isoenzyme of lactic dehydrogenase

1,6-Dihydro nicotinamide adenine dinucleotide inhibits both H-type lactic dehydrogenase and M-type lactic dehydrogenase which are isoenzymes of lactic dehydrogenase, but the degree of inhibition thereof against H-type considerably differs from that against M-type. A ratio of H-type lactic dehydrogen...

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Hauptverfasser: FUJII, KATSUMI, YOSHIMURA, SETSUKO, HORIO, TAKEKAZU, TAKAGAHARA, ISAMU, YAMAUTI, JUNITI
Format: Patent
Sprache:eng
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Zusammenfassung:1,6-Dihydro nicotinamide adenine dinucleotide inhibits both H-type lactic dehydrogenase and M-type lactic dehydrogenase which are isoenzymes of lactic dehydrogenase, but the degree of inhibition thereof against H-type considerably differs from that against M-type. A ratio of H-type lactic dehydrogenase to M-type lactic dehydrogenase in serum can be measured by utilizing the difference of inhibition degree. Therefore we can diagnose the organ with trouble.