Preparation of 5-aroyl-pyrrole compounds

A process for acylating pyrrole compounds comprising reacting an aroyl halide with the pyrrole compound in the presence of an alkyl aluminum halide. Such acylated pyrrole derivatives are useful as intermediates for the preparation of anti-inflammatory agents and as synthetic intermediates.

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Bibliographische Detailangaben
Hauptverfasser: DAGANI, MICHAEL J, KAO, JAMES T F, WIEGAND, KARL E
Format: Patent
Sprache:eng
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Zusammenfassung:A process for acylating pyrrole compounds comprising reacting an aroyl halide with the pyrrole compound in the presence of an alkyl aluminum halide. Such acylated pyrrole derivatives are useful as intermediates for the preparation of anti-inflammatory agents and as synthetic intermediates.