New O-(3-amino-2-hydroxy-propyl)-amidoxime derivatives, process for the preparation thereof and pharmaceutical compositions containing same
A compound effective in the treatment of diabetic angiopathy, i.e. a selective beta -receptor blocker has the formula (I) wherein: R2 is a hydrogen or alkyl having one to five carbon atoms, R3 is alkyl having one to five carbon atoms, cycloalkyl or phenyl optionally substituted with hydroxyl or phen...
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Zusammenfassung: | A compound effective in the treatment of diabetic angiopathy, i.e. a selective beta -receptor blocker has the formula (I) wherein: R2 is a hydrogen or alkyl having one to five carbon atoms, R3 is alkyl having one to five carbon atoms, cycloalkyl or phenyl optionally substituted with hydroxyl or phenyl, or R2 and R3 together form a five- to eight-membered ring optionally containing also other heteroatoms and/or fused with an other ring, preferably phenyl, naphthyl, quinolyl, isoquinolyl, pyridyl, pyrazolyl, R5 is hydrogen or alkyl having one to four carbon atoms, cycloalkyl or phenyl optionally substituted with halogen, alkoxy having one to four carbon atoms or alkyl having one to four carbon atoms, R6 is hydrogen, alkyl having one to four carbon atoms or phenyl, m=0, 1 or 2, and n=0, 1 or 2. |
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