Reactive derivatives of HS-group-containing polymers

A novel class of reactive derivatives of polymers containing HS-groups is disclosed in which derivatives a number of the HS-groups are converted to a disulphide group of the formula -S-S-A-Z, where A is a hydrocarbon residue having 1-10 carbon atoms and Z is a group or acid addition salts of the las...

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Bibliographische Detailangaben
Hauptverfasser: CARLSSON, JAN P E, LINDGREN, GORAN E S, DREVIN, HAKAN N Y, AXEN, ROLF E A V
Format: Patent
Sprache:eng
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Zusammenfassung:A novel class of reactive derivatives of polymers containing HS-groups is disclosed in which derivatives a number of the HS-groups are converted to a disulphide group of the formula -S-S-A-Z, where A is a hydrocarbon residue having 1-10 carbon atoms and Z is a group or acid addition salts of the last mentioned group, where n is 2 or 3, R1 is 2-pyridyl, 5-nitro-2-pyridyl or 4-pyridyl and R2 is methyl or ethyl. The novel derivatives may be used, for example, as thiolating agents or as carriers for e.g. enzymes or other proteins etc.