Process for preparing steroidal 3-oxo-4,6-dienes such as 17-hydroxy-3-oxo-17{60 -pregna-4,6-diene-21-carboxylic acid{65 -lactone

Process for preparing steroidal 3-oxo-4,6-dienes such as 17-hydroxy-3-oxo-17{60 -pregna-4,6-diene-21-carboxylic acid{65 -lactone

A process for preparing 17-hydroxy-3-oxo-17 alpha -pregna-4,6-diene-21-carboxylic acid gamma -lactone by contacting 17-hydroxy-3-oxy-17 alpha -pregna-3,5-diene-21-carboxylic acid gamma -lactone with an appropriate halogenating agent in the presence of an amine base, the corresponding hydrohalide sal...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: DRYDEN, HUGH L JR, WEBBER, GAYLE M
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
STEROIDS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator DRYDEN, HUGH L JR
WEBBER, GAYLE M
description A process for preparing 17-hydroxy-3-oxo-17 alpha -pregna-4,6-diene-21-carboxylic acid gamma -lactone by contacting 17-hydroxy-3-oxy-17 alpha -pregna-3,5-diene-21-carboxylic acid gamma -lactone with an appropriate halogenating agent in the presence of an amine base, the corresponding hydrohalide salt thereof, and approximately 1-2 molar equivalents (relative to the lactonic starting material) of water, using a cold solvent as the contact medium, and heating the resultant mixture with a dehydrohalogenating agent, is disclosed.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US4155906A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US4155906A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US4155906A3</originalsourceid><addsrcrecordid>eNqFzLEKwjAUheEuDqI-g_cBvNDYNsVRRHEU1Llck9s2UJqQVGjp4qNbUHB0Ost3_nn0unirOAQorQfn2ZE3bQWhY2-NpgYStL3FdCNRG245QHiqGiiAyLEetLf9gB8j8lHGgFOkaun3wK1ARf4xwcYoIGX0KDPAhlRnW15Gs5KawKvvLqL16Xg7nJGdLTg4UlOjK-7XVGTZLpb75L94A-wvRII</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Process for preparing steroidal 3-oxo-4,6-dienes such as 17-hydroxy-3-oxo-17{60 -pregna-4,6-diene-21-carboxylic acid{65 -lactone</title><source>esp@cenet</source><creator>DRYDEN, HUGH L JR ; WEBBER, GAYLE M</creator><creatorcontrib>DRYDEN, HUGH L JR ; WEBBER, GAYLE M</creatorcontrib><description>A process for preparing 17-hydroxy-3-oxo-17 alpha -pregna-4,6-diene-21-carboxylic acid gamma -lactone by contacting 17-hydroxy-3-oxy-17 alpha -pregna-3,5-diene-21-carboxylic acid gamma -lactone with an appropriate halogenating agent in the presence of an amine base, the corresponding hydrohalide salt thereof, and approximately 1-2 molar equivalents (relative to the lactonic starting material) of water, using a cold solvent as the contact medium, and heating the resultant mixture with a dehydrohalogenating agent, is disclosed.</description><language>eng</language><subject>CHEMISTRY ; METALLURGY ; ORGANIC CHEMISTRY ; STEROIDS</subject><creationdate>1979</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19790522&amp;DB=EPODOC&amp;CC=US&amp;NR=4155906A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25569,76552</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19790522&amp;DB=EPODOC&amp;CC=US&amp;NR=4155906A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>DRYDEN, HUGH L JR</creatorcontrib><creatorcontrib>WEBBER, GAYLE M</creatorcontrib><title>Process for preparing steroidal 3-oxo-4,6-dienes such as 17-hydroxy-3-oxo-17{60 -pregna-4,6-diene-21-carboxylic acid{65 -lactone</title><description>A process for preparing 17-hydroxy-3-oxo-17 alpha -pregna-4,6-diene-21-carboxylic acid gamma -lactone by contacting 17-hydroxy-3-oxy-17 alpha -pregna-3,5-diene-21-carboxylic acid gamma -lactone with an appropriate halogenating agent in the presence of an amine base, the corresponding hydrohalide salt thereof, and approximately 1-2 molar equivalents (relative to the lactonic starting material) of water, using a cold solvent as the contact medium, and heating the resultant mixture with a dehydrohalogenating agent, is disclosed.</description><subject>CHEMISTRY</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>STEROIDS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1979</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqFzLEKwjAUheEuDqI-g_cBvNDYNsVRRHEU1Llck9s2UJqQVGjp4qNbUHB0Ost3_nn0unirOAQorQfn2ZE3bQWhY2-NpgYStL3FdCNRG245QHiqGiiAyLEetLf9gB8j8lHGgFOkaun3wK1ARf4xwcYoIGX0KDPAhlRnW15Gs5KawKvvLqL16Xg7nJGdLTg4UlOjK-7XVGTZLpb75L94A-wvRII</recordid><startdate>19790522</startdate><enddate>19790522</enddate><creator>DRYDEN, HUGH L JR</creator><creator>WEBBER, GAYLE M</creator><scope>EVB</scope></search><sort><creationdate>19790522</creationdate><title>Process for preparing steroidal 3-oxo-4,6-dienes such as 17-hydroxy-3-oxo-17{60 -pregna-4,6-diene-21-carboxylic acid{65 -lactone</title><author>DRYDEN, HUGH L JR ; WEBBER, GAYLE M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US4155906A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1979</creationdate><topic>CHEMISTRY</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>STEROIDS</topic><toplevel>online_resources</toplevel><creatorcontrib>DRYDEN, HUGH L JR</creatorcontrib><creatorcontrib>WEBBER, GAYLE M</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DRYDEN, HUGH L JR</au><au>WEBBER, GAYLE M</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Process for preparing steroidal 3-oxo-4,6-dienes such as 17-hydroxy-3-oxo-17{60 -pregna-4,6-diene-21-carboxylic acid{65 -lactone</title><date>1979-05-22</date><risdate>1979</risdate><abstract>A process for preparing 17-hydroxy-3-oxo-17 alpha -pregna-4,6-diene-21-carboxylic acid gamma -lactone by contacting 17-hydroxy-3-oxy-17 alpha -pregna-3,5-diene-21-carboxylic acid gamma -lactone with an appropriate halogenating agent in the presence of an amine base, the corresponding hydrohalide salt thereof, and approximately 1-2 molar equivalents (relative to the lactonic starting material) of water, using a cold solvent as the contact medium, and heating the resultant mixture with a dehydrohalogenating agent, is disclosed.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_epo_espacenet_US4155906A
source esp@cenet
subjects CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
STEROIDS
title Process for preparing steroidal 3-oxo-4,6-dienes such as 17-hydroxy-3-oxo-17{60 -pregna-4,6-diene-21-carboxylic acid{65 -lactone
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-16T02%3A32%3A10IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=DRYDEN,%20HUGH%20L%20JR&rft.date=1979-05-22&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS4155906A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true