Novel prostaglandin derivatives, certain in vivo and in vitro effects thereof and processes for the preparation of same

Novel prostaglandin derivatives, certain in vivo and in vitro effects thereof and processes for the preparation of same

The novel prostaglandins PGBx are useful for a wide variety of in vivo and in vitro biological properties, including the reversal of degenerative changes in mitochondria, the protection of the heart against cardiac insults, the protection and reversal of anoxic damage to the brain, and the improveme...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: POLIS, EDITH, B. DAVID
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The novel prostaglandins PGBx are useful for a wide variety of in vivo and in vitro biological properties, including the reversal of degenerative changes in mitochondria, the protection of the heart against cardiac insults, the protection and reversal of anoxic damage to the brain, and the improvement of mammalian performance for conditioned psychological tasks. These prostaglandins PGBx are prepared, for example, by the base catalyzed reaction of PGB1.