Process for the preparation of 3-hydroxymethyl cephalosporins

A process for the preparation of a 3-hydroxymethyl cephalosporin compound which comprises selectively hydrolyzing a 3-formyloxymethyl cephalosporin compound under acidic conditions in the presence of a protic solvent whereby a 3-hydroxymethyl cephalosporin is produced.

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Bibliographische Detailangaben
Hauptverfasser: AYRES, BARRY E
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A process for the preparation of a 3-hydroxymethyl cephalosporin compound which comprises selectively hydrolyzing a 3-formyloxymethyl cephalosporin compound under acidic conditions in the presence of a protic solvent whereby a 3-hydroxymethyl cephalosporin is produced.