PROCESS FOR THE PREPARATION OF PHOSPHORUS DERIVATIVES OF SECONDARY AMMONIUM SALTS OF PENAM AND CEPHEM COMPOUNDS

Particularly valuable phosphitoamides for use in the reaction in which the 7-amino group of 7-aminocephalosporanic acid (7-aca) esters is acylated with an acyl halide. In the presence of bases, such as esters, they are easily isomerized whereby the valuable 3-cephem compounds are converted to 2-ceph...

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Hauptverfasser: PETERSEN, HENNING BORGE, NIELSEN, JORGEN ILUM, GUDDAL, ERLING, BORREVANG, POUL, FAARUP, PETER
Format: Patent
Sprache:eng
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Zusammenfassung:Particularly valuable phosphitoamides for use in the reaction in which the 7-amino group of 7-aminocephalosporanic acid (7-aca) esters is acylated with an acyl halide. In the presence of bases, such as esters, they are easily isomerized whereby the valuable 3-cephem compounds are converted to 2-cephem compounds (Machine-translation by Google Translate, not legally binding)