Process for the production of 2-amino-3-hydroxypyridines
Process for the production of 2-amino-3-hydroxypyridines of the formula wherein R1 and R2 independently of one another represent hydrogen or an alkyl group having 1 to 4 carbon atoms, wherein a furan-2-carboxylic acid of formula wherein R1 and R2 have the meaning given above, or a derivative thereof...
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Zusammenfassung: | Process for the production of 2-amino-3-hydroxypyridines of the formula wherein R1 and R2 independently of one another represent hydrogen or an alkyl group having 1 to 4 carbon atoms, wherein a furan-2-carboxylic acid of formula wherein R1 and R2 have the meaning given above, or a derivative thereof, for example a quaternary ammonium salt, an ester, an amide, a halogenide, an amidine salt, an iminoether salt or the nitrile, is reacted at a temperature of between 100 DEG and 300 DEG C in a solvent containing amide groups, in the presence of an acid catalyst, with ammonia. |
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