Use of 6-amino-9-(substituted benzyl)purines and their corresponding N{HU 1{B -oxides as coccidiostats

Novel 6-amino-9-(substituted benzyl)purines are prepared by allowing an appropriate substituted benzyl halide, e.g., a substituted benzyl chloride, to react with adenine under the appropriate conditions. Oxidation of the resulting purine derivatives yields the corresponding N1-oxides. These compound...

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Hauptverfasser: LIRA, EMIL P, BARKER, WALTER M, MCCRAE, ROBERT C
Format: Patent
Sprache:eng
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Zusammenfassung:Novel 6-amino-9-(substituted benzyl)purines are prepared by allowing an appropriate substituted benzyl halide, e.g., a substituted benzyl chloride, to react with adenine under the appropriate conditions. Oxidation of the resulting purine derivatives yields the corresponding N1-oxides. These compounds, i.e., both the purine derivatives and the N1-oxides thereof, have anti-coccidial activity and are useful for controlling cecal and/or intestinal coccidiosis when administered in minor quantities to animals, in particular to poultry, usually in admixture with animal sustenance.