PROCESS FOR PREPARING NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE

PROCESS FOR PREPARING NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE

A process for preparing nicotinamide adenine dinucleotide phosphate (NADP) by reacting nicotinamide adenine dinucleotide with adenosine triphosphate in the presence of nicotinamide adenine dinucleotide (NAD) kinase. The NAD kinase may be in the crude form and appreciable quantities of NADP are produ...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SHIMIZU Y,JA, AKIYAMA Y,JA, TATANO T,JA
Format: Patent
Sprache:eng
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
SPIRITS
VINEGAR
WINE
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Beschreibung
Zusammenfassung:A process for preparing nicotinamide adenine dinucleotide phosphate (NADP) by reacting nicotinamide adenine dinucleotide with adenosine triphosphate in the presence of nicotinamide adenine dinucleotide (NAD) kinase. The NAD kinase may be in the crude form and appreciable quantities of NADP are produced if the reaction takes place in the presence of fluoride and/or an organic sulf-hydral (SH) radical containing reagent. Good production also is achieved if the crude NAD kinase is treated with a mineral acid prior to the reaction. Exceptionally good yields are achieved if an acid-pretreated NAD kinase is used and both fluoride and an SH reagent are present during the reaction.