PHARMACEUTICAL COMPOSITIONS CONTAINING HALO-SUBSTITUTED 2-AMINO-BENZYLAMINE-AMIDES

Antitussive and respiration-stimulating pharmaceutical compositions containing as an active ingredient a compound of the formula WHEREIN Hal is chlorine or bromine, R1 is hydrogen, chlorine or bromine, R2 is alkyl of one to four carbon atoms, allyl, phenyl, chlorophenyl, methoxyphenyl, carboxyphenyl...

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Bibliographische Detailangaben
Hauptverfasser: KECK J,DT, KUGER G,DT, PUSCHMANN S,DT, MACHLEIDT H,DT, ENGELHORN R,DT, OHNACKER G,DT, ZIPP O,DT, NICKL J,DT
Format: Patent
Sprache:eng
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Zusammenfassung:Antitussive and respiration-stimulating pharmaceutical compositions containing as an active ingredient a compound of the formula WHEREIN Hal is chlorine or bromine, R1 is hydrogen, chlorine or bromine, R2 is alkyl of one to four carbon atoms, allyl, phenyl, chlorophenyl, methoxyphenyl, carboxyphenyl, carbomethoxy-phenyl, tolyl, benzyl, methoxypropyl, cyclohexyl, phenethyl or dimethylaminopropyl, R3 and R4 are each hydrogen, acetyl or benzoyl, R5 is hydrogen, alkyl of one to three carbon atoms or cyclohexyl, R6 is hydrogen, alkyl of one to three carbon atoms, hydroxyethyl, methoxypropyl, allyl, diethylaminoethyl, diethylamino-propyl, phenyl, fluorophenyl, benzyl or cyclohexyl, and N IS 1, 2 OR 3, OR A NON-TOXIC, PHARMACOLOGICALLY ACCEPTABLE ACID ADDITION SALT THEREOF; AND A METHOD OF SUPPRESSING THE COUGH REFLEX AND STIMULATING THE RESPIRATION IN A WARM-BLOODED ANIMAL THEREWITH.