1-SUBSTITUTED-5-NITROIMIDAZOL-2-YLALKYL-(N-SUBSTITUTED)-CARBAMATES

1-SUBSTITUTED-5-NITROIMIDAZOL-2-YLALKYL-(N-SUBSTITUTED)-CARBAMATES

1-Substituted-5-nitroimidazol-2-ylalkyl carbamates containing N-acyl substituents, and acid addition salts thereof are prepared from 1-substituted-5-nitroimidazoles having at the 2-position of the imidazole ring an hydroxyalkyl, mercaptoalkyl, haloalkyl, halo-carbonylalkyl or halothiocarbonyloxyalky...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: CARLSON J,CA, HOFF D,CA, ROONEY C,CA
Format: Patent
Sprache:eng
Schlagworte:
APPARATUS THEREFOR
CHEMISTRY
ELECTROFORMING
ELECTROLYTIC OR ELECTROPHORETIC PROCESSES
FODDER
FOODS OR FOODSTUFFS
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
METALLURGY
ORGANIC CHEMISTRY
PROCESSES FOR THE ELECTROLYTIC OR ELECTROPHORETIC PRODUCTIONOF COATINGS
THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
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Beschreibung
Zusammenfassung:1-Substituted-5-nitroimidazol-2-ylalkyl carbamates containing N-acyl substituents, and acid addition salts thereof are prepared from 1-substituted-5-nitroimidazoles having at the 2-position of the imidazole ring an hydroxyalkyl, mercaptoalkyl, haloalkyl, halo-carbonylalkyl or halothiocarbonyloxyalkyl radical. The 1-substituted-5-nitroimidazol-2-ylalkyl-(N-substituted)-carbamates are useful in the treatment of parasitic diseases. Antiparasitic compositions in which the active ingredient is a 1-substituted-imidazol-2-ylalkyl-(N-substituted)-carbamate are also provided.