TRIAZINE DERIVATIVES

1,252,870. Sym-Triazines. KYORIN SEIYAKU K.K. 25 March, 1969 [10 April, 1968 (2) ; 6 June, 1968], No. 28298/71. Divided out of 1,250,971. Heading C2C. Novel 2-n-butyl-4-phenethylamino-6-aminosym-triazine; 2-methyl-4,6-dipiperidino-symtriazine and 2-n-propyl-4,6-dicyclohexylaminosym-triazine are prep...

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Hauptverfasser: OKAMURA K,JA, IRIKURA T,JA, HIGO K,JA, MORINAGA F,JA, MAEDA A,JA, ABE Y,JA
Format: Patent
Sprache:eng
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Zusammenfassung:1,252,870. Sym-Triazines. KYORIN SEIYAKU K.K. 25 March, 1969 [10 April, 1968 (2) ; 6 June, 1968], No. 28298/71. Divided out of 1,250,971. Heading C2C. Novel 2-n-butyl-4-phenethylamino-6-aminosym-triazine; 2-methyl-4,6-dipiperidino-symtriazine and 2-n-propyl-4,6-dicyclohexylaminosym-triazine are prepared respectively by (1) reacting pheriethylbiguanide with an alkyl ester of valeric acid; (2) reacting 2-methyl-4-piperidino-6-halo-sym-triazine with piperidine and (3) reacting 2-n-propyl-4-cyclohexylamino-6- halo-sym-triazine with cyclohexylamine. Pharmaceutical compositions having antiinflammatory and anti-atherosclerotic properties comprise one or more of the novel compounds together with a suitable carrier for oral or parenteral administration.