PROCESS FOR THE PREPARATION OF ERGOTAMINE AND ERGOCRYPTINE

PROCESS FOR THE PREPARATION OF ERGOTAMINE AND ERGOCRYPTINE

Described is a microbiological process for the preparation of ergotamine and ergocryptine. The process is characterized in that Claviceps purpurea FI 32/17 is cultivated under aerobic conditions in submerged culture in a liquid nutrient medium containing an assimilable source of carbon, an assimilab...

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Bibliographische Detailangaben
Hauptverfasser: ANACLETO MINGHETTI, ALBA-MARIA AMICI, TULLIO SCOTTI, CELESTINO SPALLA
Format: Patent
Sprache:eng
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
SPIRITS
VINEGAR
WINE
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Beschreibung
Zusammenfassung:Described is a microbiological process for the preparation of ergotamine and ergocryptine. The process is characterized in that Claviceps purpurea FI 32/17 is cultivated under aerobic conditions in submerged culture in a liquid nutrient medium containing an assimilable source of carbon, an assimilable source of nitrogen and mineral salts. The cultivation is carried out at from 20 DEG to 35 DEG C. with a pH of from 4.5 to 6.5. Claviceps purpurea FI 32/17 has been given the index number ATCC 20102 by the American Type Culture Collection, Rockville, Maryland.