Stable aqueous glycol solution of tetracycline aluminum calcium gluconate complex having a ph of about 7. 5 to 9
The invention comprises a stable liquid composition of tetracycline, suitable for parenteral administration, comprising as a vehicle an aqueous solution containing from 30 to 80 per cent by weight of a physiologically acceptable glycol, said vehicle having dissolved therein from 10 to 125 mg/ml. of...
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| Zusammenfassung: | The invention comprises a stable liquid composition of tetracycline, suitable for parenteral administration, comprising as a vehicle an aqueous solution containing from 30 to 80 per cent by weight of a physiologically acceptable glycol, said vehicle having dissolved therein from 10 to 125 mg/ml. of tetracycline present as the tetracycline aluminium calcium gluconate complex, and said composition having a pH of 7.5 to 9.5. The composition may also contain an antioxidant, a base having a dissociation constant greater than 10-5 (to adjust the pH) or a local anaesthetic. The complex may be formed in situ in water. Specification 779,504 is referred to. |
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