RECOMBINANT THYROID-STIMULATING HORMONE RECEPTOR PROTEIN, PREPARATION METHOD AND APPLICATION THEREOF

The present invention provides a recombinant thyroid stimulating hormone receptor protein, a preparation method therefor and an application thereof. The recombinant thyroid stimulating hormone receptor protein comprises a TSHR protein extracellular segment and a TSHR protein intracellular segment. T...

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Hauptverfasser: WANG, Haihong, CHEN, Weibin, SONG, Liuwei, ZHANG, Yifei, KE, Shaojun, LIN, Qiumin, ZOU, Mengwen, ZHUANG, Cuizhen, LI, Lihua, KE, Qishen, XIONG, Junhui, LI, Huiping
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention provides a recombinant thyroid stimulating hormone receptor protein, a preparation method therefor and an application thereof. The recombinant thyroid stimulating hormone receptor protein comprises a TSHR protein extracellular segment and a TSHR protein intracellular segment. The C-terminus of the TSHR protein extracellular segment is linked to the N-terminus of the TSHR protein intracellular segment. The protein achieves extracellular soluble expression, and is high in purity, high in activity and good in stability.