CELL-DERIVED VESICLE RICH IN PROTEIN HOMEOSTASIS REGULATORS AND METHOD OF PREPARING SAME

The present disclosure relates to a cell-derived vesicle rich in intracellular protein homeostasis regulators, and to a method of preparing same. The cell-derived vesicle of the present disclosure is characterized by containing an abundance of a specific protein compared to that in a naturally secre...

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Bibliographische Detailangaben
Hauptverfasser: Bae, Shin Gyu, Han, Dong Woo, Oh, Seung Wook, Yoon, Jun Sik, Lee, Ji Hye
Format: Patent
Sprache:eng
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Zusammenfassung:The present disclosure relates to a cell-derived vesicle rich in intracellular protein homeostasis regulators, and to a method of preparing same. The cell-derived vesicle of the present disclosure is characterized by containing an abundance of a specific protein compared to that in a naturally secreted exosome or the originated cell, and by virtue of said characteristic, can be utilized for various purposes such as in a pharmaceutical composition, a diagnostic composition, and a composition for drug delivery. Using the cell-derived vesicle rich in intracellular protein homeostasis regulators and the method of preparing same of the present disclosure, it is possible to easily deliver the intracellular protein homeostasis regulators to a target, such as a cell, thereby easily maintaining protein homeostasis in cells. Accordingly, the present disclosure may also be utilized for "a use for the prevention or treatment of disease caused by a protein homeostasis regulation failure within cells" or "a use for preventing aging", and thus can be widely used in the drug industry.