FOXO1-TARGETED THERAPY FOR THE TREATMENT OF CANCER

The present disclosure provides methods of treating cancer by inhibiting the FOXO1 pathway, such as by small molecular inhibitor or RNA interference. The methods may be used to treat aggressive cancers, such as glioblastoma and basal breast cancer. Further provided herein are combination therapies f...

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Bibliographische Detailangaben
Hauptverfasser:	FLORES, David, GUNN, Bonnie, UDAWANT, Shreya, KENIRY, Megan, LOPEZ, Alma
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present disclosure provides methods of treating cancer by inhibiting the FOXO1 pathway, such as by small molecular inhibitor or RNA interference. The methods may be used to treat aggressive cancers, such as glioblastoma and basal breast cancer. Further provided herein are combination therapies for the treatment of cancer.