METHODS FOR GENERATING PARVALBUMIN-POSITIVE INTERNEURONS

The present disclosure provides a method of generating an enriched population of parvalbumin-positive interneurons. The present disclosure provides a chimeric organoid comprising an enriched population of parvalbumin-positive interneurons. The present disclosure provides methods of identifying agent...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pollen, Alexander A, Mostajo Radji, Mohammed Andres
Format: Patent
Sprache:eng
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Zusammenfassung:The present disclosure provides a method of generating an enriched population of parvalbumin-positive interneurons. The present disclosure provides a chimeric organoid comprising an enriched population of parvalbumin-positive interneurons. The present disclosure provides methods of identifying agents that modulate a feature of a parvalbumin-positive interneuron.