METHODS OF PROCESSING A BIOFLUID SAMPLE

Disclosed herein are methods and compositions for processing biofluid samples. Some such methods may include obtaining a biofluid sample from a subject having a disease state such as lung cancer. The biofluid sample may be contacted with a nanoparticles to adsorb proteins. The proteins may then be i...

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Bibliographische Detailangaben
Hauptverfasser: BLUME, John E, TROIANO, Gregory, SIDDIQUI, Asim, MANNING, William C, FAROKHZAD, Omid C, MA, Philip
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Disclosed herein are methods and compositions for processing biofluid samples. Some such methods may include obtaining a biofluid sample from a subject having a disease state such as lung cancer. The biofluid sample may be contacted with a nanoparticles to adsorb proteins. The proteins may then be ionized or contacted with a detection reagent. Also disclosed herein are compositions comprising proteins coupled to a nanoparticle upon contact of the nanoparticle with a biofluid sample from a subject having a disease.