DNA-METHYLATION-BASED CERTIFICATION OF QUALITY

The present invention relates to a method of determining the supplier from which a test animal-derived product sample originates, the method comprising the steps of:(a) determining a test methylation profile of one or more pre-selected methylation sites within the genomic material contained in the t...

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Bibliographische Detailangaben
Hauptverfasser: LYKO-TÖNGES, Sina, PFEFFERLE, Walter, NAGARAJAN, Sanjanaa, BÖHL, Florian, VENKATESH, Geetha, ROY, Suki, LYKO, Frank
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to a method of determining the supplier from which a test animal-derived product sample originates, the method comprising the steps of:(a) determining a test methylation profile of one or more pre-selected methylation sites within the genomic material contained in the test animal-derived product sample; and(b) comparing the test methylation profile determined in (a) with a panel of predetermined reference methylation profiles of the same biological taxon of the test animal from which the product sample derives, wherein each of the predetermined reference methylation profiles is from a different reference animal and/or different supplier,wherein if the test methylation profile of (a) is significantly similar to one of the predetermined reference methylation profiles, the test animal-derived product sample is confirmed of originating from a first supplier from which a first reference animal with the predetermined reference profile is obtained.