SUBSTITUTED TETRAHYDROFURANS AS MODULATORS OF SODIUM CHANNELS

SUBSTITUTED TETRAHYDROFURANS AS MODULATORS OF SODIUM CHANNELS

Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharm...

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Bibliographische Detailangaben
Hauptverfasser: Hadida Ruah, Sara S, Virani, Anisa Nizarali, Wray, Christopher, Hurley, Dennis James, Durrant, Steven John, Schmidt, Yvonne, Ahmad, Nadia M, Carvalho Meireles, Lidio Marx, Neubert, Timothy Donald, Shaw, David Matthew, Knegtel, Ronald Marcellus, Galan, Bhairavi, Pinder, Joanne Louise, Thomson, Stephen Andrew, Pullin, Robert, Chudyk, Ewa Iwona, Pontillo, Joseph, Skerratt, Sarah, Stamos, Dean, Beck, Elizabeth Mary, Etxebarria Jardi, Gorka
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.