Drug Sensitivity Prediction and Model Training Method, Storage Medium and Device

Drug Sensitivity Prediction and Model Training Method, Storage Medium and Device

A method for predicting drug sensitivity includes: acquiring gene expression information of a cell line to be tested, gene mutation information of the cell line to be tested, and structural information of a drug to be tested; calculating first correlation information between the structural informati...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: CAO, Pi, LIANG, Shuobin
Format: Patent
Sprache:eng
Schlagworte:
HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATIONTECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING ORPROCESSING OF MEDICAL OR HEALTHCARE DATA
INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS
PHYSICS
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Beschreibung
Zusammenfassung:A method for predicting drug sensitivity includes: acquiring gene expression information of a cell line to be tested, gene mutation information of the cell line to be tested, and structural information of a drug to be tested; calculating first correlation information between the structural information of the drug to be tested and the gene expression information based on a first attention model; calculating second correlation information between the structural information of the drug to be tested and the gene mutation information based on a second attention model; splicing the first correlation information and the second correlation information to obtain a splicing result; and performing a prediction processing on the splicing result based on a drug sensitivity prediction model to obtain sensitivity information of the cell line to be tested for the drug to be tested.