PROGRAMMABLE NUCLEASE DIAGNOSTIC DEVICE

Various compositions and diagnostic devices for the detection of nucleic acids are provided. Also provided are systems comprising the same, and methods of using the same. In some embodiments, compositions and devices comprise or are configured to be used in combination with one or more of a guide nu...

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Bibliographische Detailangaben
Hauptverfasser:	SHAPIRO, Sarah Jane, VEROSLOFF, Matthew, EASTMAN, Brian J, BROUGHTON, James Paul, JAIN, Sonal, STANFIELD, Emma G, FASCHING, Clare Louise, LEE, Phillip You Fai, BROWN, Amanda Claire, HAWKINS, Elizabeth M, KREINDLER, Lior, HENDRIKS, Carley Gelenter, SPRATT, Devin, SINGH, Jasmeet, HUBBELL, Sophia, NAGESH, Vaishnavi, CHEN, Janice Sha, CHING, Jesus
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TRANSPORTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	Various compositions and diagnostic devices for the detection of nucleic acids are provided. Also provided are systems comprising the same, and methods of using the same. In some embodiments, compositions and devices comprise or are configured to be used in combination with one or more of a guide nucleic acid, a programmable nuclease, and reporters. In some embodiments, presence of at least one sequence of interest is determined by detecting a signal produced upon cleavage of the reporters.