Multivalent and Multispecific DR5-Binding Fusion Proteins

Multivalent and Multispecific DR5-Binding Fusion Proteins

The disclosure relates generally to molecules that specifically engage death receptor 5 (DR5), a member of the TNF receptor superfamily (TNFRSF). More specifically the disclosure relates to multivalent and multispecific molecules that bind at least DR5.

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Bibliographische Detailangaben
Hauptverfasser: Timmer, John C, Eckelman, Brendan P, Jones, Kyle S, Razai, Amir S, Willis, Katelyn M, Hussain, Abrahim, Deveraux, Quinn
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The disclosure relates generally to molecules that specifically engage death receptor 5 (DR5), a member of the TNF receptor superfamily (TNFRSF). More specifically the disclosure relates to multivalent and multispecific molecules that bind at least DR5.