TARGETED INTERFERON ALPHA FUSION PROTEINS AND METHODS OF USE
The invention provides fusion proteins that comprise a human IFN-α2, a first antigen-binding domain capable of binding to human PD-L1, a second antigen-binding domain capable of binding to human PD-L1 and to human IFN-α2, and methods of using the same.
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| creator | RAPP, Moritz BRINKMANN, Ulrich BATES, Jack Anthony DUERR, Harald BERTOLDO, Davide SYDOW-ANDERSEN, Jasmin UMAÑA, Pablo WOLF, Monika |
| description | The invention provides fusion proteins that comprise a human IFN-α2, a first antigen-binding domain capable of binding to human PD-L1, a second antigen-binding domain capable of binding to human PD-L1 and to human IFN-α2, and methods of using the same. |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | TARGETED INTERFERON ALPHA FUSION PROTEINS AND METHODS OF USE |
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