MACHINE LEARNING FOR PREDICTING MUTATIONAL DRIVERS AND LIKELY ONSET OF FUTURE PANDEMICS

Methods disclosed herein involve forecasting mutations that will lead to pathogenic spread in the near future (e.g., 1 month, 2 months, 3 months, 4 months, or more). Using prior surveillance data including a previous spread of the pathogen, informative features of a mutation are identified for the p...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Telenti, Amalio, Maher, Michael Cyrus Riley
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Methods disclosed herein involve forecasting mutations that will lead to pathogenic spread in the near future (e.g., 1 month, 2 months, 3 months, 4 months, or more). Using prior surveillance data including a previous spread of the pathogen, informative features of a mutation are identified for the pathogen and used to predict whether the mutation is likely to lead to future pathogenic spread. Thus, this enables early identification of future strains of prevalent pathogens which can be used to develop therapeutics (e.g., vaccines) before the spread has occurred.