Stabilized Formulations Containing Anti-Interleukin-4 Receptor (IL-4R) Antibodies

The present invention provides pharmaceutical formulations comprising a human antibody that specifically binds to human interleukin-4 receptor (hIL-4R). The formulations may contain, in addition to an anti-hIL-4R antibody, at least one amino acid, at least one sugar, or at least one non-ionic surfac...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dix, Daniel B, Tang, Xiaolin
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention provides pharmaceutical formulations comprising a human antibody that specifically binds to human interleukin-4 receptor (hIL-4R). The formulations may contain, in addition to an anti-hIL-4R antibody, at least one amino acid, at least one sugar, or at least one non-ionic surfactant. The pharmaceutical formulations of the present invention exhibit a substantial degree of antibody stability after storage for several months.