ARENAVIRUS MONOCLONAL ANTIBODIES AND USES

ARENAVIRUS MONOCLONAL ANTIBODIES AND USES

Disclosed herein are compositions comprising recombinant arenavirus monoclonal antibodies and antigen-binding fragments thereof, as well as therapeutic methods using the antibodies. In some embodiments, the antibodies provide pan-arenavirus protection against a number of arenavirus types and strains...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GEISBERT, Thomas W, SAPHIRE, Erica O, HASTIE, Kathryn M, GARRY, Robert F, BRANCO, Luis M, ROBINSON, James E
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Disclosed herein are compositions comprising recombinant arenavirus monoclonal antibodies and antigen-binding fragments thereof, as well as therapeutic methods using the antibodies. In some embodiments, the antibodies provide pan-arenavirus protection against a number of arenavirus types and strains.