RECOMBINANT ANTIGEN FOR INDUCING AN IMMUNE RESPONSE AGAINST THE ZIKA VIRUS

Recombinant chimeric antigen containing a polypeptide comprises amino acids 2 to 104 of the zika virus capsid protein or a polypeptide with an amino acid sequence with at least 90% identity with such capsid protein region. Vaccine composition that comprises such recombinant chimeric antigen and a ph...

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Hauptverfasser: ROMERO FERNÁNDEZ, Yaremis, BRUNO DARDER, Andy Jesús, PÉREZ FUENTES, Yusleidi de la Caridad, HERMIDA CRUZ, Lisset, GUILLEN NIETO, Gerardo Enrique, COBAS ACOSTA, Karem, SUZARTE PORTAL, Edith, VALDES PRADO, Iris, LAZO VAZQUEZ, Laura, GIL GONZÁLEZ, Lázaro
Format: Patent
Sprache:eng
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Zusammenfassung:Recombinant chimeric antigen containing a polypeptide comprises amino acids 2 to 104 of the zika virus capsid protein or a polypeptide with an amino acid sequence with at least 90% identity with such capsid protein region. Vaccine composition that comprises such recombinant chimeric antigen and a pharmaceutically approved adjuvant. Use of the recombinant chimeric antigen containing a polypeptide comprises amino acids 2 to 104 of the zika virus capsid protein or a polypeptide with an amino acid sequence with at least 90% identity with such capsid protein region, for manufacturing a medicament for the induction of immune response against zika virus. The invention revels also a method for the induction of immune response against zika virus wherein this recombinant chimeric antigen is administered.