METHOD OF DIAGNOSING AND TREATING CHRONIC KIDNEY DISEASE

A method of diagnosing and/or treating stage 3 or stage 4 chronic kidney disease (CKD) is provided herein, where a proUGN concentration level of 2.241 ng/ml or higher is indicative of stage 3 or stage 4 CKD. Additionally, a method of diagnosing and/or treating pre-CKD is also provided herein, where...

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Hauptverfasser: KEMPER, Nicholas, CARRITHERS, Brennan M, MORRISON, Luke E, CARRITHERS, Stephen L, CARRITHERS, Aaron L
Format: Patent
Sprache:eng
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Zusammenfassung:A method of diagnosing and/or treating stage 3 or stage 4 chronic kidney disease (CKD) is provided herein, where a proUGN concentration level of 2.241 ng/ml or higher is indicative of stage 3 or stage 4 CKD. Additionally, a method of diagnosing and/or treating pre-CKD is also provided herein, where a proUGN concentration level of 2.05 ng/ml to and including 2.24 ng/ml in a biological sample is indicative of pre-CKD and that a patient is at risk of developing CKD. The methods may comprise measuring the amount of proUGN in a biological sample of the patient and/or administering a CKD-therapeutic agent and/or providing lifestyle and/or dietary modifications to the patient.