GENE-MODIFYING ENDONUCLEASES

The disclosure relates to compositions and methods that modify target nucleic acids, as well as methods of detecting nucleic acids. Various compositions are described herein, including compositions comprising endonucleases, endonuclease systems, and chimeric proteins having the endonuclease and a nu...

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Bibliographische Detailangaben
Hauptverfasser: AL-SHAYEB, Basem, SHARMA, Kushagra, JAVANMARDI, Mohammad Kamyab, BORRAJO, Jacob
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The disclosure relates to compositions and methods that modify target nucleic acids, as well as methods of detecting nucleic acids. Various compositions are described herein, including compositions comprising endonucleases, endonuclease systems, and chimeric proteins having the endonuclease and a nucleic-acid modulating domain or a nucleic acid modifying domain.