MULTISPECIFIC ANTIBODIES FOR IMMUNO-ONCOLOGY

Multispecific antibody having a binding site for ICOS and a binding site for a second antigen, e.g., an immune checkpoint molecule such as PD-L1. Use of the multispecific antibody in immuno-oncology, including for treatment of solid tumours.

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Bibliographische Detailangaben
Hauptverfasser:	MCCOURT, Matthew John, VAN KRINKS, Cassandra, CAMPBELL, Jamie, DEANTONIO, Cecilia, LEE, E-Chiang, KOSMAC, Miha, GALLAGHER, Thomas, ALI, Mohammed Hanif, SANDY, Nikole, GERMASCHEWSKI, Volker, ARKINSTALL, Stephen John, GILLIES, Stephen Douglas, KIRBY, Ian, SAINSON, Richard Charles Alfred
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	Multispecific antibody having a binding site for ICOS and a binding site for a second antigen, e.g., an immune checkpoint molecule such as PD-L1. Use of the multispecific antibody in immuno-oncology, including for treatment of solid tumours.