NOVEL COMPOUNDS, COMPOSITIONS, AND THERAPEUTIC USES THEREOF

The present invention relates to a compound of the Formula:or a pharmaceutically acceptable salt thereof.The compound of the present invention inhibits Polθ. This novel therapeutic compound is therefore useful for the treatment and/or prevention of diseases and conditions in which Polθ activity is i...

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Bibliographische Detailangaben
Hauptverfasser:	Flanagan, Stuart Robert, Malassis, Julien Gilbert Jacques, Yule, Ian Andrew, Corella, Andrea Guerrero, Hollick, Jonathan, Smith, Matthew Raymond, Bentley, Jonathan Mark
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention relates to a compound of the Formula:or a pharmaceutically acceptable salt thereof.The compound of the present invention inhibits Polθ. This novel therapeutic compound is therefore useful for the treatment and/or prevention of diseases and conditions in which Polθ activity is implicated, such as, for example but not limited to, the treatment and/or prevention of cancer. The present invention also relates to pharmaceutical compositions comprising the novel therapeutic compound defined herein, to processes for synthesising the compound and to their use for the treatment of diseases and/or conditions in which Polθ activity is implicated.